About the Applications and Factors to Be Considered when Choosing Sterile Syringe Filter

Sterile Syringe Filters are fast, convenient and reliable small-volume sample filtration devices that are routinely used in laboratories. It saves much time and effort, no need to clean filter or change filter membrane. With light weight, high cleanliness and stylish design, the sterile syringe filter are mainly used for samples pre-filtration, sterilization filtration of laboratory biological fluids, culture media and media additives. Today, HAWACH will discuss the applications and how to choose a suitable sterile syringe filters.

Applications of Sterile Syringe Filter

Reliable, fast and convenient, the sterile syringe filter is mainly used for sample pre-clarification, particle removal, liquid and gas sterilization filtration, laboratory biological fluid, culture medium and medium additives sterilization filtration etc.

1. Ambient air, exhaust gas, and water quality analysis.
2. The medical industry needs autoclave sterilization water injection, large infusion solution to filter out particles. It can improve the internal quality of medicines and the pass rate of clarity.
3. Detection and analysis of raw materials, finished products and semi-finished products of food, beverages and medicines.
4. Educational and commercial R&D laboratory water and organic solution filtration.
5. Teaching, quality inspection, quality control; sample preparation for chromatography and mass spectrometry. Sterile Syringe FiltersSterile Syringe FiltersSterile Syringe Filters

Factors to consider when choosing a sterile syringe filter

Avoiding other impurities introduction during the filtration process is necessary, when the syringe filter processes chromatographic samples. Such impurities can be: the filter membrane or shell material shed particles and carry them into the filtrate. Therefore, the filter membrane and housing structure materials are very important. We need to choose the filter membranes based on the samples’ properties.

■Hydrophilic samples: the hydrophilic membranes should be chosen, which have affinity for water and are suitable for filtering water-based solutions. Available filter membranes are: mixed cellulose ester MCE, polyethersulfone PES, nylon, hydrophilic PTFE, hydrophilic PVDF and so on. For instance, the nylon filter membrane has ultra-low extract content and high protein binding capacity. It is recommended to filter alcohols, cryoprotectants, such as DMSO, glycerin and solvents.
■Strong corrosive organic solvent: we generally use inert membrane, such as PTFE, PVDF, polypropylene PP and other materials filter membrane.
■Protein solution: we suggest the filter membrane with low protein adsorption, such as hydrophilic PVDF, PES filter membrane.
■Ion chromatography: it’s considered the PES filter membrane is more suitable for filtering low inorganic ions solutions. PES membrane has the lowest protein binding capacity, ultra-low extract content and high flow rate, making it the first choice for filtering media.
■If there are too many impurities in the sample and the filtering resistance is too large, you need to consider using a syringe filter with pre-filtering. The effect of 33mm is the most ideal.

Besides the above factore, we also need to consider the sample’s volume when purchasing a syringe filter. Usually when the sample size is less than 2ml, a 4mm diameter micro filter (customizable) is used; the sample size is between 2-10ml, 13mm For the diameter filter, when the sample volume is greater than 10ml, use a 25mm diameter filter; when the sample volume exceeds 100ml, use a 33mm diameter syringe filter.

HAWACH provides various syringe fiters for different usages and the advantages are as follows:

Various membrane types: MCE, NYLON, PVDF, PES, PTFE, CA
Different diameter specifications are available: 13MM, 25MM and 33MM
Different membrane pore size: 0.22μm, 0.45μm
Quick and easy to use, the media falls within the limit
No heat source
Single package

Whether your research requires pre-filtration, sample preparation, sterile filtration, laboratory filtration, or exhaust, the HAWACH syringe filter is a must-have appliance in your laboratory.

Click here to know Overview and How to Use Sterile Syringe Filters

09/16/2021