In general, the syringe filter is used before the sample solution enters the liquid chromatography. It filters out some particles that may block the system and the chromatography column. If impurities exist in the sample and solvent, it will not only damage the chromatographic instrument and column, but also have a great impact on the analysis results. The organic phase syringe filter has a good effect on protecting the chromatographic column and the chromatographic system from contamination, and also it can improve the sensitivity and accuracy of the analysis results. But how to choose filter membranes of different materials? HAWACH describes its membranes in details for your reference.
The universal filter membrane is suitable for the filtration of most sample solutions and solvents. The filter membrane itself has hydrophobic properties, but it is also suitable for the filtration of aqueous solutions and organic solvents, and it is often used for the filtration of HPLC and GC samples and solvents.
The hydrophobic filter membrane is suitable for the filtration of organic solvent media samples (including strong acids and strong bases) and organic solvents. Although it has a hydrophobic filter, it can also be made hydrophilic by adding ethanol and deionized water. It is used in filtration of all organic solutions, especially strong solvents that other filter membranes cannot tolerate.
Polyvinylidene fluoride (PVDF)
Hydrophobic filter membrane with very low protein adsorption, low resistance and fast filtration, is especially suitable for the filtration and sterilization of biological samples. In addition, it also has high chemical compatibility, suitable for the filtration of most media.
Hydrophilic filter membrane has uniform pore size, high porosity, low resistance, fast filtration speed, and very small adsorption, which is mainly used to filter out particles and bacteria in biological samples and water-soluble samples.
Hydrophilic filter membrane has low resistance, fast filtration speed, low protein adsorption, especially suitable for the filtration of viscous biological and cell tissue samples. In addition, it also has good permeability, suitable for rapid filtration of large volume of aqueous samples. Its applications cover the low protein adsorption and high drug compatibility, specially designed for biochemical, inspection, pharmaceutical and sterilization filtration devices.
Glass fiber (GF)
Universal pre-filtration membrane with a pore size of 1.0 μm, is suitable for high particle content or viscous sample filtration; compared with syringe filter without GF pre-filtration membrane, the processing capacity is increased by 2-4 times.
If the above cannot meet your requirement, please contact HAWACH team.