What Factors Should be Considered When Choosing Syringe Filter?

The main function of the microporous filtration membrane and syringe filter is to trap and filtering of the particles, bacteria and other impurities from the gas phase or liquid phase for separation, purification and purification purposes.

The following factors should be considered when selecting a syringe filter:

1. Filter media (chemical compatibility):
The first factor to be considered is the chemical compatibility of the filter media.
If the filter is resistant to organic solvents such as acids and alkalis. See our syringe filter chemical compatibility table for details of each.
2. Diameter
For column systems using 3um or larger particle size, 0.45um syringe filter or membrane can be used; for chromatographic system with less than 3um packing, or chromatographic system involving microbial growth, it is recommended A 0.20 um filter was used. For viscous solutions, pre-filtration can be carried out using a 1-5 um filter and then continually filtered with the corresponding filter.
3. Characteristics of the sample
1) Hydrophilic sample: A hydrophilic membrane is used. It has an affinity for aqueous based samples. Membranes also used such as: mixed cellulose esters, polyethersulfone (PES), Nylon, and the like.
2) Strong corrosive organic solvent: a hydrophobic film is generally used. Filters such as PTFE, polypropylene (PP)
3) Protein solution: Select a low protein adsorption filter, such as a PVDF filter.
4) Ion Chromatography: PES membranes are generally considered to be suitable for filtration of solutions with low inorganic ions.

4. Sample Volume
When selecting the syringe filter, consider the volume of the sample (that is, what size of the syringe filter is selected): Generally, when the sample amount is less than 2 ml, a 4 mm diameter micro-filter is used. The sample volume is between 2-10ml, and the 13mm diameter filter is suggested to use. When the sample amount is more than 10ml, the 25mm diameter syringe filter is suggested to use.