The Features, Applications And Use Notes Of Sterile Syringe Filter

Syringe filters are widely used in laboratories and are designed to provide fast, efficient filtration solutions for water and organic solutions. These units are made of various membrane filters with polypropylene housings, and a special injection molding process increases burst pressure as well as filtration speed. These syringe filters are suitable for many applications and can be used in pharmaceutical, environmental, biotechnology, food/beverage, agricultural product testing laboratories.Disposable syringe filters are more convenient to use. If it is an aqueous sample, you can use cellulose or polyethersulfone directly and choose PTFE, if the sample is acidic or alkaline. If it is a general organic filter, Just use nylon or regenerated cellulose.

Sterile syringe filter

Sterile syringe filter is a filter that is attached to the front end of a syringe, which is suitable for pre-filtered samples and solvents to remove particulate contaminants and protect the instrument. Ion chromatography, commonly used in environmental analysis, also requires that inorganic pollutants cannot be introduced in sample pretreatment. It’s an important step to filter sample solutions in the process of sample pretreatment. The filter adopts advanced testing methods and production technology to produce high-quality sterilized syringe filters, and the product quality far exceeds other peers.

 Sterile Hydrophilic PTFE Syringe FiltersSterile PVDF Syringe FiltersSterile MCE Syringe Filters

Sterile syringe filters, including gas filters or liquid filters, should be tested for integrity according to the sterile filter integrity test procedures before and after use. After the integrity test, the membranes and filters used for aseptic production need to be sterilized. The sterilization methods of sterilized syringe filters are divided into steam sterilization and ethylene oxide gas sterilization. The general method is steam sterilization. For in-line steam sterilization of sterile syringe filters, the differential pressure before and after the filter should be monitored during sterilization.

The general sterile syringe filter should be kept in an upright position, and should not be placed obliquely or lying down. The sterilization time, pressure and temperature should be recorded during the sterilization process. A sterile syringe filter cannot filter different products at the same time, but can be used to filter multiple batches of the same product, but must be tested for integrity. A sterile syringe filter can be used for no more than 1 working day. In the process of use, if the filtration rate suddenly becomes faster or too slow, it means that the membrane has been damaged. Then replace it with a new membrane and do the experiment again.

Main applications of sterile syringe filter

Sterilized syringe filters are suitable for liquid medicine, electronics, semiconductor industry, microelectronics water filtration, tissue culture medium, beverages, high-purity chemicals, water and organic solution mobile phase filtration. There is no need to change the filter membrane and clean the filter, saving working time. It is mainly used in the following 6 aspects.
1. Ultra-fast filtration of tissue culture medium, additives and other aqueous solutions;
2. Applications that require extremely low protein adsorption can improve the yield of precious components;
3. Biological and pharmaceutical sterilization and filtration;
4. Terminal filtration of high-purity water in the electronics industry;
5. Terminal filtration of ink;
6. Food: terminal filtration of beverages, wine, etc.  

Precautions for the use of sterilized syringe filters

1. Do not use a syringe smaller than 10cc, because the small volume of the column tube may cause the pressure to exceed the upper limit, resulting in damage to the filter membrane or personal injury.
2. In the laboratory, it’s for one-time use.
3. Part of the filtrate at the beginning should be discarded. Taking 25mm as an example, the first 1mL of the filtrate should be discarded or the filter should be pre-cleaned with 1 to 2mL of solution.

Click here to know How to Sterilize Syringe Filters? Several Common Materials And Advantage For Syringe Filter

10/14/2022